Duke won the only meeting with Louisville this season, taking down the Cardinals by 11 in Louisville back in December. The Blue Devils will once again be without Cooper Flagg, He did not play against North Carolina after injuring his ankle and they will rest him to get ready for the Big Dance.Since that loss to Duke, Louisville has gone 22-2 SU, and they haven’t lost a home or neutral-site game. The Cardinals are on an eleven game winning streak. Duke is shorthanded and is facing a red hot team with an experienced backcourt. I like the Cardinals to keep this one close with a chance to get the upset late.

Play on Louisville. This is a 3% play