Arizona will be without three important players in center Rodney Hudson, tight end Maxx Williams and star pass-rusher Chandler Jones, who has five sacks and 14 QB hits on the year.
Kyler Murray isn't 100 percent, either and the Browns defense will be putting a ton of pressure on him today. The Cards, 1-5 ATS in their past six vs. teams with a winning record, have struggled against the run this season, allowing 139.0 yards per game, and that plays right into Cleveland's hands with Kareem Hunt. The Browns rushing attack has piled up 639 rush yards the last three weeks. Also, Cleveland got lit up for 40+ pts last week and I look for them to bounce back at home with a dominant performance.