The 49ers are coming into this game with a 5-3 record this season and they have lost their last 3 straight games after starting the year 5-0. They have not been playing well in their last 3 games and they are going to be on the road here but they are also coming out of their bye week and they have been getting a lot healthier with their 2 weeks off. They also acquired Chase Young in a trade who has not made his debut with the team yet and he is sure to make a much needed impact on this defense. They are going up against a Jaguars team that is 6-2 this season and has been very hot recently as they have won their last 5 straight games. They are also coming out of their bye week here and will be at home but as good as they have been recently, they do not have the talent that a healthy 49ers team has and the Jags are due for a loss in this game. The 49ers still have one of the best teams in the NFL when everyone is healthy and they are due for a much needed bounce back win here out of their bye week with everyone coming back for this game. The 49ers will cover the spread in this game.