Creighton is coming into this game with a 24-10 record this season and they were 15-5 in their conference. They are coming off of an 82-66 loss against St John's in their last game, but they have been hot coming into this tournament as they have won 4 of their last 5 games. They are going up against a Louisville team that is 27-7 this season and they were 18-2 in their conference. They are coming off of a 73-62 loss against Duke in their last game, but they have also been very hot recently as they have won 11 of their last 12 games. They had a great season in the ACC, but they were not very good in their non-conference schedule. They were only 7-4 in non-conference games this season and they did not have a Big East opponent on their schedule. They also lost all 4 of their non-conference games against teams who did not make the tournament. Both of these teams have been similar this season, but Creighton does have the better shooting percentage both from the field and from 3. They have also defended those shots better this season and have a slight advantage at the rim with their rebounding as well. Creighton will cover the spread in this game.