Luis Castillo has become an ace this season. He is 6-1 with a 2.20 ERA. Castillo has been especially dominant at home compiling a 1.87 ERA at Great American Ball Park. Castillo is in great current form, too, with a 1.56 ERA during his past three starts. The Astros have the added disadvantage of never having faced Castillo.

Keep in mind, too, Houston has been minus three injured stars - Jose Altuve, George Springer and Carlos Correa.

But what about Astros starter Wade Miley? He certainly doesn't have the star quality of Castillo. But Miley has been good for more than a year now with a 2.85 ERA during his last 30 starts. The 32-year-old Miley has become a highly reliable, solid starter late in his career. The lefty has given up three runs or fewer in 13 of his 14 starts this year. Miley is coming off six scoreless innings against the Orioles.

Great American Ball Park is an excellent hitter's park. But like Castillo, Miley has shown he can pitch well there going 4-0 with a 2.27 ERA in six career starts. Cincinnati ranks 21st in slugging percentage against southpaws.

There is no DH, which is a huge plus for the Under. So are the relief pitchers. The Astros and Reds each rank in the top-four in bullpen ERA. The Astros have all of their top bullpen arms rested and ready. So do the Reds.