This is more than just a division game, but a real rivalry. It remains to be seen just how much of a dropoff there is between Nick Foles and rookie Gardner Minshew. Foles has mostly been a backup in his career, although a top-notch one. Minshew demonstrated tremendous poise in replacing Foles against the Chiefs last Sunday completing 22 of 25 passes for 275 with two touchdowns and one interception. 
The Jaguars are run-oriented. Leonard Fournette is their featured player not the quarterback. 

Minshew has underrated wide receivers. He just has to manage this game, though, for the Jaguars to hang in. The Jaguars have an upper level defense. They were sixth in defensive efficiency last season. Cornerback Jalen Ramsey is one of the few who can hang against DeAndre Hopkins. 
The Texans are playing on a short week after an exhausting road game against the Saints this past Monday night. The Texans have not shored up their porous pass protection particularly at right tackle. Deshaun Watson was sacked six times by New Orleans and endured 11 hits. The Jaguars have held Watson to two touchdown passes in three games and just 5.8 yards per pass attempt. The Jaguars also have recorded 21 sacks in their last four games against the Texans.