Now that the Chargers' outstanding starting offensive tackles, Rashawn Slater and Joe Alt are healthy, Jim Harbaugh can run a more balanced offense and not be so run-heavy. It also helps that Justin Herbert seems healed from an ankle sprain. Herbert is an elite passer when given adequate pass protection and being healthy.

Herbert has mediocre receivers to throw to, but the bar is set very low here. The Cardinals are a bottom-six defense with multiple injuries. They lack a pass rush and rank 29th in run defense. Herbert should have favorable play-call situations all game against this foe.

I expect the Cardinals' offense to get in gear. Kyler Murray has the mobility and the skill position talent. Look for Marvin Harrison Jr. to be among his weapons for this game.

The Cardinals have had to play the Packers and 49ers on the road during their past two games. Now they are home. That should make a difference.

The Chargers have excellent defensive numbers. The only good quarterback, though, the Chargers have faced this season is Patrick Mahomes. The Chargers have been fortunate to go against the following QB's: Gardner Minshew, Bryce Young, Justin Fields and Bo Nix. So their defensive numbers are skewed.