25* Clemson Tigers
Tonight I am taking the Clemson Tigers as small home underdogs against the Louisville Cardinals. Tonight is the night that Lousiville has met their match and will not be able to run up and down the field like a video game. Deshaun Watson and company are going to be able to put up more than their fair share of points and the defense isn't going to shut down the Lousiville offense but they will contain them. We get great value on this line because of how well Louisville started and how Clemson hasn't been firing on all cylinders. We don't even need any points as Clemson is going to win outright. Take Clemson to the bank!