The Louisville Cardinals have opened the season 1-1 after a dominant 35-21 win over Western Kentucky in their first game only to take a 47-34 loss to Miami last time out. It was not all doom and gloom for the Cardinals though as they racked up 516 offensive yards and outgained the Hurricanes by 31 yards. It could have been a very different game if not for turnovers (two fumbles and a thrown interception cost them dearly).

Now, the Cardinals' explosive offense will face a tough test against an elite Pitt defense, but I think we're getting good value on Louisville. Pittsburgh might be 2-0 SU, but it failed to cover the 21.5-point spread last time out against Syracuse, winning 21-10.

Panthers are 8-20 ATS in their last 28 games as a home favorite.

8* play on Louisville.