The Colts didn't look all that impressive in a home win over the banged up Bengals on Wild Card Weekend, and I think they will be in way over their heads here in Denver. The Broncos have been dominating with their defense and running game, while Peyton Manning has been uncharacteristically quiet. I wouldn't count on another quiet game for Manning though, and I expect this to be a blowout.

Here are my keys to the game:

1. Quick Start - The Broncos jumped out to an early 27-7 lead on the Colts when these teams played in Week 1, but Indy rallied to make the game interesting late. I don't think the Colts will be able to come back if they go down early here in this game.

2. Colts Running Game - Indy ran for just 64 yards on 34 carries (2.1 yards per carry) in their win over Cinci last week.

3. X-Factor - The Broncos are 20-8-1 ATS in their last 29 games on grass.

Selection: This is a play on the Denver Broncos (10*)