The set-up: The Phillies took two of three in Washington over the weekend, but they lost the final 8-6 last night. The Yankees were also involved in a high-scoring, extra-inning slug-fest with Tampa, as they ultimately came out on the short-end of a 7-6 setback. Suffice it to say, I think runs are going to be much harder to come by in the opener of this interleague series. The visitors go with Jonathan Loaisiga, while the home side goes with Vince Velasquez.

The pitchers: Loasigia is so far 1-0 with a 3.12 ERA. Loasiga's debut saw him shut down the Rays, but he'd come back down to Earth in his second start by allowing three runs off six hits with four strikeouts over 3.2 innings in a no-decision against the Mariners last week. Loasigia has shown great potential and I think he'll match his counterpart inning for inning.

Velasquez is so far 5-7 with a 4.82 ERA. Velasquez most recently gave up four runs off four hits over 6.1 innings while also striking out eight in a no-decision to St. Louis on Tuesday. Note that Velasquez owns a decent 1.28 WHIP to go along with a 97/29 K:BB over 80.1 innings.

The pick: Take it for what you will, but New York has already seen the total dip below the posted number in seven of nine inter-league contests this season. While these teams come in off a couple of high-scoring series, the opener of this one points to the "under" as the correct call.