The set-up: LA catches a break here after Jon Gruden traded defensive star Khalil Mack to the Bears for some draft picks. The Rams had the league's highest scoring offense last year, so we can absolutely expect the visitors to push the pace and open up the playbook from start to finish.

The teams: LA went 2-2 in the preseason, but it would rest most of its starters over those four games. Jared Goff and Todd Gurley are back and they now welcome dangerous WR Brandin Cooks to the mix. The Rams spent a ton of money on the defensive side of the ball in the offseason, but I think the unit will struggle on opening night.

Jordy Nelson will be the main WR in Oakland now that Michael Crabtree is gone. Amari Cooper will also be hoping for a much better season after totalling just 680 yards in 14 games last season.

The pick: Take it for what you will as well, but Oakland has seen the total go "over" the number in seven of its last nine Week 1 home games when the total in the contest is between 47 and 50 points. With LA pushing the tempo of this one and with the home side having no choice but to match pace, I'm banking on this one flying "over" sooner, rather than later.