The set-up: This series features a couple of lop-sided mis-matches on the mound and there's no doubt that this is one of them. In fact I think that the talent-gap is so large on the mound this afternoon, that I have no issues at all in laying the the 1.5 runs for the much more reasonable price. The visitors go with Gerritt Cole, while the home side goes with Daniel Norris.

The pitchers: Cole is so far 13-5 with a 2.86 ERA. He most recently gave up two runs off six hits with three walks while striking out nine over 5.2 innings in a win over the Angels in his last start. Cole has been sharp on the road as well, going 6-3 with a 2.81 ERA.

Norris is so far 0-3 with a 5.47 ERA. He has struggled in his limited time so far this season and there's no reason not to think that that pattern of futility won't get carried over here as well. Note that he's a terrible 0-2 with a 5.40 ERA in all "day" games also.

The pick: Take it for what you will as well, but the Astros are 7-2 in their last nine American League road games in which they're a favorite in the -200 to -300 range. Look for Cole to dominate from the start and for Norris to get the hook early and lay the 1.5 runs on the Astros.