The set-up: This series features a couple of competitive match-ups on the mound and there's no question that this is one of them. The visitors hand the ball to ace Jacob deGrom, while the home side goes with ace Chris Sale.

The pitchers: deGrom is so far 8-9 with a 1.71 ERA. The Mets right-hander has been nearly perfect this season and he's been especially tough on the road where he's a "lights out" 5-3 with a 1.66 ERA.

Sale is so far 12-4 with a 1.96 ERA. He returned on Tuesday to throw a scoreless frame against Toronto, giving up one hit and striking out two. Sale's been out since August 12th, but he's re-habed successfully, made a successful first appearance and now he's been given the green light to make his first start.

The pick: Note that Sale is 4-2 with a 1.92 ERA at home and 5-1 with a 1.55 ERA in all "day" games. Take it for what you will as well, but Boston has seen the total go "under" the number in seven of its last ten American League home day games in which it's a favorite in the -125 to -200 range. This number is high, play the "under."