The set-up: UC Irvine clearly can't be taken lightly after knocking off K-State in the opening round 70-64. The Anteaters have averaged 107.4 points per 100 possessions, while allowing 97.4 points per 100 possessions. Note that UC Irvine has held its opposition to just 40.7 percent shooting from inside the arc, which ranks first in the country. The Ducks smashed Wisconsin 72-54, but I think they'll have their hands full today with this aggressive Anteaters defense. Overall the Ducks average 108.9 points per 100 possessions, while allowing only 92.2.

The pick: Take it for what you will as well, but UC Irvine is 4-1 ATS this year as an underdog, while Oregon is just 1-3 ATS in its last four as a neutral court favorite in the 3.5 to six points range. Bank on the Anteaters going down with a fight, but don't be shocked by the outright either. Either way though, grab the points.

10* play