The set-up: I like the Pirates to build off their 4-1 win over the Giants in yesterday's series opener. San Francisco has struggled with offensive consistency to open the 2019 campaign, and facing a motivated Jameson Taillon at home isn't what the doctor ordered to get it turned around. The visitors counter with the volatile Derek Holland.

The pitchers: Holland (1-2, 4.09 ERA) most recently gave up four runs off four hits with four walks over six innings in a loss to Colorado on Sunday. The 32 year old has allowed a home run in each of his four outings thus far this season.

Taillon (0-2, 3.43) gave up three runs over six innings while striking out four in a no-decision vs. Chicago on Monday. Taillon was 14-10 with a 3.20 ERA last year, including posting a sharp 2.99 ERA in all "day" games.

The pick: Take it for what you will as well, but San Fran is an atrocious 22-46 (-13.8 units) in its last 68 as a road underdog in the +125 to +175 range, while Pittsburgh is 27-8 (+13.8 units) in its last 35 as a favorite of -150 or more. This one has rout written all over it.

Pittsburgh Pirates

10* play