The set-up: There was an over night pitching change for the Angels in this one, which makes my play on Chicago even stronger in my opinion. The visitor hand the ball to Cam Bedrosian, while the home side counters with Jon Lester (note that this is a make-up game from a postponed contest from April.

The pitchers: Bedrosian (2-3, 3.08 ERA) comes out of the bullpen to make this difficult spot start; note that he's 1-2 with a 3.95 ERA on the road.

Lester (3-4, 3.59) opened the year on fire, but he'll be looking to rebound after allowing a season-high seven earned runs over five innings in a loss to the Astros on Tuesday.

The pick: After winning two straight, I think the Angels take a step back in this NL format/ballpark. And after getting swept in three straight in St. Louis over the weekend, I look for the home side (and Lester) to come in extremely focused. Everything points to a rout in my opinion.

Chicago Cubs

10* play