The set-up: I think the Bills are going to "go through the motions" in this difficult road venue. Buffalo head coach Sean McDermott's team was just 6-10 last year and the Bills are 4-5 in the pre-season under his direction. Carolina was just 7-9 under Ron Rivera last season, but overall he's 19-14 in the preseason.

The pick: The Bills already have a solid 24-16 home win under their belts vs. the Colts last Thursday anyways. The Panthers scored the 23-13 win in Chicago last Thursday, but I don't think they'll take the foot off on the gas in this home field situation (rookie defender Brian Burns had two sacks). I think Buffalo packs up its tents early; play the home side on the money-line.

Carolina Panthers, Moneyline 10* play