The Bills have a few things to be thankful for this Thanksgiving. 1. They are healthy, a novel concept in the NFL. 2. The Saints are not. Missing major players in the offensive line, and with Kamara missing and Ingram questionable, the Saints running game has taken a big hit. 3. Siemian is showing his true colors. Siemian’s completion rate is in the 50’s, very low considering the protection he has received, and without Kamara as a run threat and a passing out, he will be even more limited.

The Bills were embarrassed last week by the Colts, their usually solid run defense torn to shreds. The Saints, usually even better against the run, were also pummeled, with much of that coming from opposing QB Hurts. Allen can run. Can he duplicate Hurts’ success? Allen has struggled of late and has not lived up to expectations. This game provides an opportunity for bounce back, if he can control an ugly pattern of turnovers. He has been protected well this season, and the 22nd rated Saints passing defense could be picked on.

I like Buffalo in this game. The Bills have a winning record on the road, the Saints have struggled at home. With a depleted running game, Siemian up against a tough Bills passing defense and with the Saints’ depleted O line, I just don’t see where the Saints’ points are coming from. This is the perfect opportunity for Allen and the Bills to shine. Take the Bills to win and cover.