Teams after playing Seattle are 23-49 including nine straight losses. That says to fade Arizona. We like the fact the Niners have no pressure. This will especially help their underachieving QB Colin Kaepernick.

The Cardinals have clinched a playoff spot, and they probably won't be able to be higher than a fifth seed. We know Jim Harbaugh has had his ups and downs this year in the 49ers locker room. But his teams have had a lot of success together, so we look for his players to rally around a guy likely coaching his last game as head coach of San Francisco.

Arizona has scored just two offensive touchdowns in the past 22 quarters, dating back to the second half against the Lions in the 10th game. With Ryan Lindley at QB, do not look for that number to get better. RB Frank Gore is hot for San Francisco and Arizona is ice cold on run defense. Kaepernick has plenty of motivation to finish the season with consecutive strong efforts. It gets ugly.