Major
(NFL) Philadelphia vs. Indianapolis,
Total: 54.50 | -115.00 Over
Result: Loss
When a team averages more than 400 total yards per game and turnover rate is (-2) or worse it has gone UNDER 43-18. This is actually a rare case of it applying to both teams, which when applied had gone under all four times since 1978.

Philly minus two OL starters Pro Bowl left guard Evan Mathis and RT Allen Barbre. To the credit of Eagles head coach Chip Kelly, he does make adjustments rather than force his players to adapt. This would seem like a good enough reason to slow things down.