I like Syracuse to take care of business on the road in this game. I know the Orange lost the last time these teams met, but they were dominating that game in the first half. Pittsburgh is without one of the best players in college basketball and could have several backups out due to COVID-19 protocols. The Panthers have not played in more than a week and will likely be rusty in this game. Syracuse is going to be focused after blowing the big lead in the last meeting. The Orange have covered in five of the last six head-to-head games.