The KC Chiefs have leaned on their highly-ranked defense this season, finishing in the top five for Defense and excelling in points allowed per game. Against Buffalo, Mahomes' ability to control the clock and capitalize on key drives gives Kansas City an edge, especially with Hunt contributing effectively in the run game. The Chiefs’ balanced offensive attack will stay undefeated with a win on Sunday. With Buffalo facing injuries in their secondary and short preparation time after a Monday game, KC gets our call here.