This is a bad time for the Chargers to play a team like SanFran off a BYE week, and Herbert has been relatively awful this year in comparison to last season. 49ers defense has been superb, and the effectiveness of Austin Ekeler will not be enough to get past this strong DLine that has been given a chance to get healthy with the BYE. The passing defense has been trash for Chargers, and JC Jackson who was brought in from New England to be the Defacto #1 CB had been TORCHED this season. 49ers roll through Chargers whos is in a look-ahead spot as they play the Chiefs next weekend.

Official Play: 49ers -7

Side Bet: Over 45 points

Side Bet: Deebo Samuel TD

Side Bet: Jimmy G over 1.5 passing TDs

Side Bet: Justin Herbert Over 0.5 Interceptions