Jacksonville is set up very well in this game as they have been in London for a week already and are accustomed to the time change. Jacksonville has a strong fanbase in London as the Jaguars have played the most games in London.

Buffalo is coming off a BIG win against their division opponents Miami who had been undefeated. Buffalo now travels to London to face the Jaguars in a bad situational spot.

Take the points with the Jaguars who could be a live dog to win this game outright.

Pick: Jacksonville Jaguars +5.5