Home field advantage: The game is being played at Scott Stadium in Charlottesville, where Virginia holds a 4-2 record against Louisville historically. Playing at home could give the Cavaliers an edge.

Virginia's strong start: The Cavaliers are off to their best start under coach Tony Elliott at 4-1 overall and 2-0 in ACC play. They have momentum on their side.

Louisville's recent struggles: The Cardinals have lost two straight games and are falling out of the AP Top 25 rankings5. They may lack confidence coming into this matchup.

Virginia's defensive strength: The Cavaliers are allowing just 23.8 points per game and are strong against the run. This could make it difficult for Louisville to pull away.