The Bengals are 10-4 ATS as road 'dogs and have shown marked improvement this season. Joe Burrow is living up to his hype and status as the No. 1 overall draft pick. He has solid skill position help and Cincinnati's offensive line is getting better. 
The Colts defense surrendered 32 points to the Browns last week despite Baker Mayfield playing at less than 100 percent and Cleveland missing Nick Chubb. Indy's defense isn't the same without star linebacker Darius Leonard, who is doubtful to play here. 
Cincinnati's defense is another facet that has improved. The Bengals sunk a lot of money into upgrading their defense. They finally got back their best defensive lineman, Geno Atkins, last week. 
The Colts don't have the offense to lay this big of a number. The Colts rank second-to-last in yards per rush at 3.6 per carry. Yet the Colts have to remain a ground-based, two-wide receiver, two-tight end offense because of wide receiver injuries and the steep decline of Philip Rivers, who has become one of the least effective starting QB's in the league.