The set-up: Both teams come in rolling. Carolina enters off three straight wins, most recently a 42-28 victory over Tampa Bay, while Pittsburgh has won four straight, most recently a 23-16 win over Baltimore. These teams are very similar, with dynamic and capable QB's who each have plenty of weapons to utilize. But Newton has struggled against the elite defenses throughout his career and I think that trend carries over here at Heinz Field.

The pick: Take it for what you will as well the Panthers are a terrible 3-8 ATS in their last 11 after two or more consecutive SU victories, while Pittsburgh is a perfect 2-0 ATS in its last two Thursday night contests. Lay the points and expect a rout.