The set-up: Andrew Luck and the Colts have sure looked impressive over the last month, but I believe their story comes to and tonight. The Chiefs can't play a lick of defense, but they haven't had to with their dynamic offense, led by Patrick Mahomes, who set offensive records this year. With a week off to focus and game-plan though, I absolutely expect the Chiefs' to also "step up" their game defensively as well. Indianapolis averaged 27.1 PPG, while allowing 21.5. The Chiefs averaged 35.3 PPG though and allowed 26.3.

The pick: Mahomes though is the difference maker in my opinion. He finished with 5,097 passing yards with a sharp 50/12 TD/INT. Take it for what you will as well, but despite the Colts recent "up-tick" in play, they're still only 14-17 ATS in their last 31 as an underdog, while Kansas City is 13-5 ATS in its last 18 after scoring 30 points or more in its last game. In my estimation, everything points to the Colts running out gas this weekend. I'm laying they points.

10* play