The set-up: The Cubs have lost eight of 11 to open the year, but they have a chance to win their first series of the season with a victory today. Chicago won the series opener 10-0, before falling 5-2 on Wednesday. While he struggled in his first start, I think that Cubs' starter Jose Quintana will settle down here and deliver the goods.

The pitchers: The Pirates hand the ball to Joe Musgrove (1-0, 0.00 ERA) who struck out eight over seven scoreless vs. the light-hitting Reds earlier.

Quintana (0-1, 10.29) comes off an outing to forget in which he allowed eight runs over three innings to the Brewers. Quintana has enjoyed plenty of success vs. the Bucs though, having gone 1-1 with a 2.89 ERA in five career starts vs. them.

The pick: Keep your eyes on Cubs' slugger Jason Heyward, who has a .371 average after three hits yesterday, including a solo home run. Good price on the hungry home side here. Lay it.

Chicago Cubs

10* play