The set-up: These two teams enter hungry. That's where the similarities end though, as Cincinnati is essentially in a "must win" scenario at 0-2, while the Bills are looking to build off their improbable 2-0 start. Neither team will be lacking for motivation here and as such, I'm expecting this contest to be extremely wide open. After a tight 21-20 setback in Seattle and then a 41-17 loss to San Francisco, the pressure is clearly on Bengals' QB Andy Dalton to step up and deliver here.

The pick: The Bills have gotten great play on both sides of the ball as well, especially from QB Josh Allen, who led his team on four TD drives in their Week 2 victory against the Giants. From a situational stand point, I think it definitely sets up as a "shootout," but also note that the Bengals have seen the total go over the number in six of their last seven as a road dog of seven points or less, while Buffalo has seen the total soar over in nine of its last 12 at home. This number is a litre low.

8* play on the over Bengals/Bills.