The set-up: The Jays lost two of three in Tampa to open, including allowing a 4-2 lead going into the bottom of the 9th evaporate. Yes, the Nationals are down some men, but I still think the defending champs will find a way to get the job done here once it's all said and done. The Jays hand the ball to Trent Thornton, who was 6-9 with a 4.84 ERA last year and while he had a decent spring, I still think he's in over his head in this difficult road venue.

The pick: The home side counters with Anibal Sanchez, who was 11-8 with a 3.85 ERA last year and who gave up three runs while striking out eight in an instrasquad matchup in his final tuneup. Note as well that he was particularly good in all "night" games last year, going 7-5 with a 3.10 ERA. And finally note that the Nats are 7-2 in their last nine interleague night home games as a favorite in the -105 to -135 range. Lay the price.

10* GAME OF THE WEEK on the Nationals.