The set-up: Both teams are 2-0 SU, but Buffalo is 0-2 ATS. Here is a stat which this pick is primarily based upon:

How NFL teams that start 0-2 ATS perform in Week 3:

Last 4 Seasons: 22-7 ATS (75.9%)
Last 10 Seasons: 47-28 ATS (62.7%)

The pick: Additionally note that Buffalo is 4-1 ATS in its last five as a favorite, while the Rams are just 2-6 ATS in their last eight on the road when facing a team with a winning record. I think the Rams' inefficiences on the defensive end come back to haunt them here. Lay the points.

This is an 8* ATS SITUATIONAL DESTRUCTION on the Buffalo Bills.