The set-up: After seeing a bunch of favorites get the hook early on Friday, the Virginia Cavaliers will be cautious not to follow the same fate here in what is actually a very favorable matchup for them. Note that the Cavs are still the reigning NCAA Champion, because last year's tournament was cancelled. The Cavs had a small COVID issue, and one player will not be at the game today, but they've won seven of their last ten and three in a row.

The pick: Ohio has won nine of its last ten games. It's had to deal with COVID issues this year as well. The Bobcats lack the depth and experience a this level though, and note that the Cavs are 10-3 straight-up in their last 13 NCAA Tournament games and 9-3-1 ATS in their last 13 after an ATS loss. The Cavs are well-coached and their defense is suffocating. Look for UVA to pull away for a comfortable win and cover on Saturday night.

This is a 10* FIRST ROUND GAME OF THE YEAR on UVA.