This line is based upon preseason expectations but not reality. The 49ers as a 10 point favorite after only scoring 10 points against Chicago? The 49ers QB Trey Lance doesn't have a track record of success just yet. And for what it's worth, the 49ers just are 8-24-1 ATS in their last 33 games as a home favorite. On the other side the Seahawks are 12-5 ATS in their last 17 games as a road underdog.