The Buffalo Bills can clinch the AFC East here with a win, and they come off a bye so they have been preparing for the Niners, and we expect a good effort here. Purdy is questionable with a shoulder injury. He was limited in practice Wednesday, so who knows if he plays here, but this Niner team was struggling with Purdy when healthy. McCaffery is back but we like Buffalo here, we think they got some well needed rest and are ready to go on SNF.