Louisville at Houston 8:00 ET
Cougars (+) over Cardinals- Since their loss to Clemson the first weekend in October Louisville knew they had to be perfect the rest of the way and so far they have been, reeling off five straight wins. Houston had such promise as they opened the season with a win over Oklahoma and stayed unbeaten (5-0) until they were sunk at Navy 46-40 and then two weeks later by SMU and are 0-6 ATS since October 1. The Cardinals are explosive but Houston has the offensive fire-power to counter Louisville and are confident enough after pulling of last season's upset 34-31. This time with the points at home! Take HOUSTON!