Carolina at San Francisco 4:25 ET
49ers (+) over Panthers- As my buddy handicapper and politician asked me 'who quarterbacks the 49ers?' So, I dug deep and found out that it is Brian Hoyer and I have to figure that is better then Blane Gabbert anyway. Carolina of course will have a 'repaired' Cam Newton and exciting wide receiver/running back and return man Christian McCaffrey. But, San Francisco has an answer on the ground with Carlos Hyde who is ready to make his mark with head coach Kyle Shananhan. How bad can Hoyer be he was 10-5-1 ATS with the Browns but the Niners are 2-13 ATS in the last 15 meetings. Be careful. Take SAN FRANCISCO!