San Francisco at New Orleans 4:25 ET
49ers (+) over Saints- Well, the Saints came marching in and rolled into Tampa Bay and out with after thrashing the Buccaneers. It wasn't even a game! The Bucc's had a total of five rushing attempts with only four by running backs while New Orleans forced Tom Brady to play his first ever game with multiple interceptions without a TD pass. San Francisco is a mess with a rash of injuries and load of positive COVID results they have been very inconsistent. Nick Mullins is making his fourth start at QB and has is 68.4% for 1,143 yards and five TD's and five int's. Despite what going on SF has the No. 7 ranked Defense allowing just 324 yards and surprising their offense has played steady and ranked No. 13 with 374 yards a game. New Orleans should come back to the pack after a near perfect game against Tampa and the Niners should rebound from losses to Seattle and Green Bay. Take SAN FRANCISCO!