New England at Indianapolis 8:15 ET
Colts (-) over Patriots- I believe that New England's Mac Jones will throw more than three passes this week as the conditions will be perfect in domed Lucas Oil Stadium. The Colts will attempt to run the ball against the No. 3 defense in the NFL allowing just 310 yards per game while Indianapolis is No. 2 running for 152 yards a game lead by the league's top runner Jonathan Taylor who has 1,348 yards and 16 touchdowns. Taylor has run for 100 yards seven times this season and each time the Colts posted a victory. Indy leads the NFL in takeaways with 28 while the Patriots have 26 of their own. The home team is 5-1 ATS in this series and the Colts who didn't play last week are 4-1-1 ATS after a bye week and is 12-4-1 ATS at home against teams teams with winning records. Take INDIANAPOLIS!