The 49ers come into this game having lost two of their last three, however their defense is only giving up 18 PPG, and that my friends will be the difference maker in this one. THe SF 4 upfront guys will be pressuring Goff all night. In their earlier matchup this season he completed only 13 passes for a career-low 78 yards.
The combination of him having a bruised thumb isn't going to help as I see SF cruising to a big win here on Saturday night.