The Giants couldn't pick a better team to open their home season than the Kansas City Royals. Kansas City comes in at 1-6 this season and will send Brad Keller to the mound. He is 0-1 this season with a 3.86 ERA. San Francisco evened their record at 3-3 after a 16-3 win over the White Sox. Alex Cobb makes the start for the Giants with a 0-0 record and a 2.45 ERA. The Giants' offense came alive against the Sox, putting up 31 runs with 38 hits in three games. The Royals were just the opposite against Toronto, being outscored 13-4 in three games. For the season. the Royals have scored just 17 runs in seven games. Cobb had an ERA under 3.00 at home last season. Keller, on the road, had an ERA close to six. The Royals are struggling to score and the Giants' offense had an explosion against the Sox. Take the Giants at home in this one.

Play on San Francisco on the run-line.