It would be hard to imagine the 49ers not emerging victorious on Saturday but the question is "by how much?" First off, there is a huge risk of heavy rain and wind, making for the likelihood of a run-dominated game. The Giants ran 60% of the time in their last game and have had plenty of success with it, averaging 160+ yards in their last three games. The Seahawks' defense doesn't handle the run at all well, so the 49ers would be wise to take advantage irregardless of the weather. Seattle, and especially Walker has had rush success lately, as the Seahawks have put up even more yards than the 49ers on the ground L3 Seattle will likely have a tougher time moving the ball against an excellent SF rush defense.
The 49er's pass defense, while not exactly struggling lately, has given up more passing yards, a higher completion % and more points lately. Smith has excellent targets, but his star is not nearly as shiny in recent games, and he will face formidable pass pressure from the 49ers. Purdy has improved each week and is off a passer rating of 115 in his last three games, but he doesn't exactly air it out. He is still very much a rookie, and the Seahawks' pass defense has been much better recently, with 5 sacks last week and a passer rating allowed of just 65 in their last three games.
Considering the field conditions, I think this game will be closer than expected. Carroll will have the Seahawks prepared, and certainly the team from Emerald City are no strangers to rain. While a win is not likely for the Seahawks, neither is a blow out. Take Seattle plus the points